If, as many religions state, God is everything, then there is no fundamental difference between God and the world (universe, multiverse). This reduces the question if God exists to a self-referential question without external reference point. The question is wrong, and therefore irrelevant.
If God is separate from universe, current scientific success and understanding of the universe strongly suggests that such a God doesn't have any effect on the workings of the universe or the human condition, thus making the answer to the question irrelevant.
Putting it plain and simple: God does not and cannot answer any of my questions, nor can any combination of lesser gods or goddesses; Amen!